Tolfenamic acid CAS 13710-19-5

CAS:13710-19-5

Fọọmu Molecular:C14H12ClNO2

Ìwọ̀n Molikula:261.7

EINECS:237-264-3

Awọn itumọ ọrọ sisọ:LABOTEST-BB LT00772313; Acid TOLFENAMIC; 2- ((3-chloro-2-methylphenyl) amino) -benzoicaci; n- (2-methyl-3-chlorophenyl) anthranilicacid; 2- (3-CHLORO-O-TOLUIDINO) BENZOIC ACID; 2 (3-CHLORO-2-METHYLANILINO) BENZOIC ACID; 2-[(3-CHLORO-2-METHYLPHENYL)AMINO]BENZOIC ACID; Tolfedine; 2-[(3-Chloro-o-tolyl) amino] benzoic acid; n- (3-chloro-o-tolyl) -anthranilicaci; AWỌN ỌMỌRỌ; n-(3-chloro-o-tolyl) -anthranilicacid

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ọja Tags

Kini Tolfenamic acid CAS 13710-19-5?

Tolfenamic acid jẹ oogun egboogi-iredodo ti kii ṣe sitẹriọdu ti a lo lọpọlọpọ ni adaṣe ile-iwosan bi antipyretic, analgesic, ati oogun egboogi-iredodo. O jẹ itọsẹ ti ortho aminobenzoic acid, Tolfenamic acid, ti GEA ti dagbasoke ni Denmark. Ni egboogi-iredodo ti o lagbara ati awọn ipa analgesic pẹlu awọn ipa ẹgbẹ ti o kere ju.

Sipesifikesonu

Nkan	Sipesifikesonu
Oju omi farabale	405.4± 40.0 °C(Asọtẹlẹ)
iwuwo	1.2037 (iṣiro ti o ni inira)
MW	261.7
pKa	3.66± 0.36 (Asọtẹlẹ)
EINECS	223-123-3
Oju omi farabale	405.4± 40.0 °C(Asọtẹlẹ)

Ohun elo

Tolfenamic acid ṣe ipa antipyretic rẹ ati awọn ipa analgesic nipa didi iṣelọpọ ti cyclooxygenase. Lọwọlọwọ, o ti wa ni o kun lo ninu awọn itọju ti arun bi rheumatoid Àgì ati migraine ni isẹgun ise. Ni awọn ọdun aipẹ, awọn ọjọgbọn ni ile ati ni ilu okeere ti ṣe awọn iwadii lọpọlọpọ lori eyi ati rii pe Tolfenamic acid ṣe ipa pataki ninu didaduro idagbasoke sẹẹli tumo, iṣakoso apoptosis sẹẹli tumo, kikọlu pẹlu ami ifihan sẹẹli tumo, ṣiṣe iṣakoso iṣẹ ti awọn oncogenes ati awọn Jiini suppressor tumo, ati idinamọ angiogenesis tumo.