Celastrol CAS 34157-83-0

CAS:34157-83-0

Fọọmu Molecular:C29H38O4

Ìwúwo Molikula:450.61

EINECS:636-472-5

Awọn itumọ ọrọ sisọ:CELASTROL (SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(Jọwọ IPE); (20R) -3-Hydroxy-2-oxo-24-nor-D: A-friedolean-1 (10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1 (10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

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Kini Celastrol CAS 34157-83-0?

Celastrol jẹ insoluble ninu omi, tiotuka ni dimethyl sulfoxide ati ethanol anhydrous. Ti o wa lati awọn eroja ti nṣiṣe lọwọ egboogi-akàn ninu awọn ohun ọgbin bii Thunder God Vine ati South Snake Vine ninu idile Celastraceae. Inhibitor proteasome ti o munadoko, timo lati fa apoptosis sẹẹli alakan nipasẹ didaduro iṣẹ ṣiṣe proteasome

Sipesifikesonu

Nkan	Sipesifikesonu
Oju omi farabale	645.7± 55.0 °C(Asọtẹlẹ)
iwuwo	1.2
Ojuami yo	219-230°C
pKa	4.78± 0.70 (Asọtẹlẹ)
o pọju	424nm (MeOH) (tan.)
Awọn ipo ipamọ	-20°C

Ohun elo

A lo Celastrol fun ipinnu akoonu / idanimọ / awọn adanwo oogun, bbl Awọn ipa elegbogi: O ni awọn ohun-ini antioxidant ti o lagbara, awọn ipa angiogenesis anti-akàn, ati awọn ipa rheumatoid. Inhibitor proteasome ti o munadoko, timo lati fa apoptosis sẹẹli alakan nipasẹ didaduro iṣẹ ṣiṣe proteasome