2,5-Dimethoxybenzaldehyde CAS 93-02-7
2,5-Dimethoxybenzaldehyde jẹ ina lulú kristali ofeefee kan pẹlu iwuwo molikula kan ti 166.18 ati aaye farabale ti 146°C. O ti wa ni tiotuka ni Organic olomi bi ethanol ati ether. O ti wa ni o kun lo bi awọn kan elegbogi agbedemeji.
| Nkan | ITOJU |
| Ifarahan | Grẹy to ofeefee ri to |
| NMR | Ni ibamu |
| Mimo | > 98% |
| Ojuami yo | 46-48°C (tan.) |
| Omi akoonu | <0.5% |
Ni afikun si oxidized tabi dinku si 2,5-dimethoxybenzoic acid, benzonitrile tabi ọti benzyl, 2,5-dimethoxybenzaldehyde funrararẹ tun ni iye ohun elo alailẹgbẹ. Nipa fesi pẹlu awọn oludoti pẹlu awọn oriṣi ti awọn ẹgbẹ iṣẹ ṣiṣe, awọn ohun elo oogun pẹlu awọn ẹya oriṣiriṣi ati awọn ipa oriṣiriṣi le ṣee gba. Arun Pakinsini (PD) jẹ arun neurodegenerative ti o wọpọ, ati awọn ami aisan akọkọ rẹ pẹlu gbigbọn iṣan, rigidity, awọn iṣoro gbigbe, iduro ara ati awọn rudurudu iwọntunwọnsi gbigbe. Idagbasoke siwaju yoo tun yorisi idanimọ, akiyesi, awọn rudurudu iranti ati iyawere gbangba. Ni lọwọlọwọ, itọju PD ni akọkọ pẹlu itọju oogun, itọju abẹ ati itọju jiini. Ninu itọju oogun, a rii pe phenamidine ni ipa rere lori PD, pẹlu majele kekere ati ailewu to dara, ati pe iṣelọpọ ti phenamidine nilo lilo 2,5-dimethoxybenzaldehyde bi ohun elo ibẹrẹ.
Ni ibamu si awọn kolaginni ọna royin ninu awọn litireso, 2,5-dimethoxybenzaldehyde wa ni o kun gba nipa fesi 1,4-dimethoxybenzene pẹlu kan formylation oluranlowo. Awọn aṣoju fọọmu pẹlu (1) adalu 1,1-dichloromethyl ether ati titanium tetrachloride; (2) adalu N, N-dimethylformamide ati irawọ owurọ oxychloride, adalu N, N-dimethylformamide ati oxalyl kiloraidi; (3) adalu N, N-dimethylformamide ati thionyl kiloraidi tabi adalu urotropine ati iṣuu magnẹsia kiloraidi. Sibẹsibẹ, awọn ọna wọnyi nilo lilo titobi titanium tetrachloride, irawọ owurọ oxychloride tabi thionyl kiloraidi. Awọn reagents wọnyi jẹ riru ati irọrun ti bajẹ, ati pe iye nla ti gaasi hydrochloric acid ti wa ni idasilẹ lakoko iṣesi, eyiti kii ṣe ore ayika ati pe o ni awọn ibeere giga fun ilana iṣiṣẹ naa.
Ọna tuntun ti a ti dabaa. Ọna yii nlo 1,4-dimethoxybenzene ati formaldehyde bi awọn ohun elo aise, ati pe o ṣe ifasilẹ idapọ photooxidative ni iwaju atẹgun ati ayase labẹ itanna bulu ina lati ṣapọpọ 2,5-dimethoxybenzaldehyde daradara. Ọna yii nlo atẹgun tabi afẹfẹ bi oxidant, ko ṣe agbejade gaasi ekikan, ati pe o jẹ ore ayika. Ni afikun, ọna yii nlo koluboti olowo poku bi ayase, eyiti o jẹ kekere ni idiyele ati pe o dara fun ohun elo ile-iṣẹ.
25kgs / ilu, 9tons / 20'epo
25kgs / apo, 20tons / 20'epo
2,5-Dimethoxybenzaldehyde CAS 93-02-7
2,5-Dimethoxybenzaldehyde CAS 93-02-7
